Research areas

ICR-Imperial partnerships

Collaborations

Publications

Our Research

Prevention and early detection of cancer improves quality of life and saves lives.

Epidemiological research plays a pivotal role in identification of causes of cancer, and the translation of those findings into cancer prevention through studies aimed at risk assessment, understanding natural history of cancer and evaluating biological targets for prevention. 

CEPRU uses innovative approaches in epidemiological studies, including molecular and imaging technologies and geospatial analyses, to establish cancer causes, characterise risk at the individual and population level, understand the natural history of cancer, and identify biological targets of prevention. This research can inform XXXX

XXXX especially for aggressive cancers and those affecting younger populations (e.g., triple-negative breast cancer, early onset colorectal cancer). CEPRU will also focus on understanding long-term treatment effects in cancer survivors, including secondary cancers and lifestyle's role in improving outcomes.

CEPRU main research areas

Risk and Protective Factor Identification

  • Genomics:
    –   Breast cancer GWAS- Confluence

  • Exposomics:
    –   Discern/ EPIC – Proteomics
    –   Geospatial analyses

Risk Assessment

  • XXXX
    –   XXXX

  • XXXX
    –   XXXX

Cancer risk prediction

  • Breast cancer:
    -   BCN Generations study – development and validation of integrated breast cancer risk prediction tools in the UK –
    incl. mammography and digital path
    -   B2RISK and BCRF- hormone levels to T-C model
    -   Confluence Project– PRS for breast cancer

  • Colorectal cancer:
    -   Model validation in Generations study

  • Multi-cancer:
    -   CRUK CD3 program on multi cancer risk prediction in asymptomatic and symptomatic populations in the UK

XXXX Heading missing XXX

  • Investigating inequalities through population trends in cancer incidence and mortality

  • Breast cancer etiologic heterogeneity

  • Cancer and risk factor trends

Natural history of cancer

  • Molecular and digital pathology:
    -   BBD and breast cancer
    -   Colorectal ???
    - Diabetes and cancer cohort consortium project

Cancer Survivorship

  • Lifestyle factors

  • Long term effects of treatment